學習經歷
1997-2001 河北大學⚅,學士
2002-2005 河北大學🍼,碩士
2005-2008 河北農業大學🛺,博士
工作經歷
2008-2011 河北農業大學EON体育4注册,講師
2011-2018 河北農業大學EON体育4注册,副教授
2018- 河北農業大學EON体育4注册👩🏻,教授
2014-2015 美國伊利諾伊大學香檳分校作物科學系🔻,訪問學者
榮譽稱號及社會兼職
河北省微生物學會副理事長、農業微生物專業委員會主任,2023-2028🧑🦱;
教學工作
本科生課程:
1. 專業基礎課《基礎微生物學》、《藥學微生物學》、《微生物學與免疫學》
2. 專業選修課《微生物工程》
研究生課程:
《生物學專業英語》
主要研究方向及領域
微生物資源與利用
寄主-病原物互作分子機製
主持課題
1.玉米大斑病菌效應蛋白StCFEM12靶向ZmFd1促進寄主感病的分子機製. 國家自然科學基金(32472501), 2025-2028, 主持
2.玉米大斑病生防菌篩選及其互作機製研究. 國家重點研發計劃子課題(2023YFD1401503), 2023-2027, 主持
3. 玉米大斑病菌StLCB1和StLCB2基因調控附著胞發育的分子機製及其dsRNA對病菌的抑製作用. 中央引導地方科技發展資金項目(246Z6505G), 2024-2027, 主持
4. 內生微生物組生態調控玉米鐮孢菌病害的機製與應用. 河北省重點研發計劃(20326503D), 2020-2022, 主持
5. 玉米大斑病菌轉錄調控因子StFlo8調控極性生長的分子機製. 河北省自然科學基金面上項目(C2020204172), 2020-2022, 主持
6. 夏玉米病害無害化防控及化肥農藥協同增效模式創新. 國家重點研發計劃子課題(2018YFD0200607-02), 2018-2020, 主持
7. 鈣/鈣調素依賴性蛋白激酶(CaMK)基因家族調控玉米大斑病菌致病性的功能解析. 河北省自然科學基金(C2016204160), 2016-2018, 主持
8. StPKA-c調控玉米大斑病菌侵染能力的分子機製. 國家自然科學基金(31301616), 2014-2016, 主持
出版教材著作
主編👩🏻🌾,冀中南夏玉米化肥農藥減施增效技術. 河北大學出版社🙍🏻♀️,2024.
代表性學術成果
研究論文(*通訊作者):
1.Liu Yuwei, Liu Jiayue, Sun Mingqing, Mao Yanan, Feng Shang, Shen Shen, Liu Tingting, Cao Zhiyan, Li Zhiyong, Hao Zhimin*, Dong Jingao. The genome sequencing and comparative genomics analysis of Rhizoctonia solani reveals a novel effector family owning a uinque domain in Basidiomycetes. International Journal of Biological Macromolecules, 2024, 278: 134328.
2.Li Pan, Shen Shen, Jia Jingzhe, Sun Hehe, Zhu Hang, Wei Ning, Yu Bo, Aamir Sohail, Wu Di, Zeng Fanli, Hao Zhimin*, Dong Jingao. The catalytic subunit of type 2A protein phosphatase negatively regulates conidiation and melanin biosynthesis in Setosphaeria turcica. International Journal of Biological Macromolecules, 2024, 266: 131149.
3.Li Pan, Sun Hehe, Han Xinpeng, Long Feng, Shen Shen, Li Zhiyong, Hao Zhimin*, Dong Jingao. The septin gene StSep4 contributes to the pathogenicity of Setosphaeria turcica by regulating the morphology, cell wall integrity and pathogenic factor biosynthesis. Journal of Agricultural and Food Chemistry, 2023, 71(49): 19568-19580.
4.Li Pan, Zhu Hang, Wang Chengze, Shen Shen, Zeng Fanli, Sohail Aamir, Wang Yanhui, Hao Zhimin*, Dong Jingao. StRAB4 gene is required for filamentous growth, conidial development, and pathogenicity in Setosphaeria turcica. Frontiers in Microbiology, 2024, 14: 1302081.
5.Liu Jiayue, Feng Shang, Liu Tingting, Yanan Mao, Shen Shen, Liu Yuwei, Hao Zhimin*, Li Zhiyong. Molecular characterization revealed the role of thaumatin-like proteins of Rhizoctonia solani AG4-JY in inducing maize disease resistance. Frontiers in Microbiology, 2024, 15: 1377726.
6.Liu Yuwei, Jia Lixia, Zhou Cheng, Mao Yanan, Shen Shen, Hao Zhimin*, Li Zhiyong. Genome resource of Rhizoctonia solani anastomosis group 4 strain AG4-JY, a pathomycete of sheath blight of foxtail millet. Plant Disease, 2023,107(3): 926-928.
7.Han Shipeng, Sun Donghui, Zhou Cheng, Wang Qing, Chen Jie, He Yunzhuan, Hao Zhimin*. First report of Botryosphaeria dothidea causing stem blight of Dioscorea oppositifolia in China. Plant Disease, 2023, 107(7): 2232.
8.Hao Zhimin, Liu Yuwei, Liu Jiayue, Zhou Cheng, Shen Shen, Dong Jingao, LI Zhiyong. First report of Rhizoctonia solani AG-4 HG-III causing sheath blight on foxtail millet in China. Plant Disease, 2023,107(7): 2223.
9.Li Pan, Sun Hehe, Dong Jingao, Hao Zhimin*. Protein kinase C is required for the pathogenicity of Setosphaeria turcica on maize. Journal of Plant Pathology, 2023, 105(3): 683-693.
10.Liu Yuwei, Shen Shen, Hao Zhimin*, Wang Qing, Zhang Yumei, Zhao Yulan, Tong Yameng, Zeng Fanli, Dong Jingao. Protein kinase A participates in hyphal and appressorial development by targeting Efg1-mediated transcription of a Rab GTPase in Setosphaeria turcica. Molecular Plant Pathology, 2022, 23:1608-1619.
11.Han Shipeng, Wang Qing, Zhang Shuo, Jin Xi, Hao Zhimin*, He Yunzhuan. First report of Alternaria tenuissima causing brown spot disease on Angelica dahurica in China. Plant Disease, 2022,106(1): 332.
12.Wang Jianxia, Long Feng, Zhu Hang, Zhang Yan, Wu Jianying, Shen Shen, Dong Jingao, Hao Zhimin*. Bioinformatic analysis and functional characterization of CFEM proteins in Setosphaeria turcica. Journal of Integrative Agriculture, 2021, 20(9): 2438-2449.
13.Zeng Fanli, Meng Yanan, Hao Zhimin(共一), Li Pan, Shen Shen, Cao Zhiyan, Dong Jingao. Setosphaeria turcica ATR turns off appressorium-mediated maize infection and triggers melanin-involved self protection in response to genotoxic stress. Molecular Plant Pathology, 2020, 21: 401-414.
14.Li Pan, Liu Xueqin, Hao Zhimin*, Jia Yanrong, Zhao Xiangdong, Xie Debao, Dong Jingao, Zeng Fanli. Dual repressive function by Cip1, a budding yeast analog of p21, in cell-cycle START regulation. Frontiers in Microbiology, 2020, 11: 1623.
15.Zhang Hong, Huang Xinzheng, Jing Weixia, Liu Danfeng, Khalid Hussain Dhiloo, Hao Zhimin*, Zhang Yongjun. Two farnesyl pyrophosphate synthases, GhFPS1-2, in Gossypium hirsutum are involved in the biosynthesis of farnesol to attract parasitoid wasps. Journal of Integrative Agriculture, 2020, 19(9): 2274-2285.
16.Liang Hailong, Wang Qing, Shen Shen, Jia Yanrong, Li Pan, Zeng Fanli, Hao Zhimin*, Dong Jingao. Yeast surface displayed xylanase is an efficient strategy to induce corn defence response. Biotechnology & Biotechnological Equipment, 2020, 34(1): 665-672.
17.王程澤, 張燕, 付偉, 賈京哲, 董金皋, 申珅, 郝誌敏*. 玉米ACO基因家族生物信息學分析及表達模式分析. 中國農業科學, 2024, 57(7): 1308-1318.
18.孫賀賀, 王程澤, 賈京哲, 申珅, 郝誌敏*, 董金皋. 玉米大斑病菌轉錄調節因子StFlo8互作蛋白的篩選與鑒定. 農業生物技術學報, 2024, 32(6): 1385-1392.
19.錢欣雨, 王會敏, 候美玲, 申珅, 郝誌敏*, 董金皋. 玉米內生菌YY1菌株抗菌蛋白的穩定性和活性組分分析. 植物保護學報, 2023, 50(3): 725-732.
20.武建穎, 張燕, 孫賀賀, 趙玉蘭, 董金皋, 申珅. 郝誌敏*. 玉米大斑病菌蛋白激酶 A 催化亞基 StPKA-C1/C2的表達與互作蛋白篩選. 農業生物技術學報, 2022, 30(10): 1976-1986.
21.李天聰, 朱行, 魏寧, 龍鳳, 武建穎, 張燕, 申珅, 郝誌敏*, 董金皋. 玉米大斑病菌SC35同源基因表達規律與互作分析. 中國農業科學, 2021, 54(4): 733-743.
22.劉彥策, 王會敏, 錢欣雨, 李慧穎, 申珅, 郝誌敏*, 董金皋. 玉米內生菌L10的分離、鑒定及拮抗活性分析. 植物保護學報, 2021, 48(3): 630-637.
23.王建霞, 王擎, 趙玉蘭, 李天聰, 龍鳳, 朱行, 申珅, 郝誌敏*. 玉米大斑病菌GATA轉錄因子氮源響應表達模式分析. 農業生物技術學報, 2020, 28(7): 1297-1305.
24.龍鳳, 王擎, 朱行, 王建霞, 申珅, 劉寧, 郝誌敏*, 董金皋. 玉米大斑病菌Septin基因家族的鑒定與表達模式分析. 中國農業科學, 2020, 53(24): 5017-5026.
發明專利:
1. 郝誌敏🛳,孫東輝🐈,申珅🧑🌾,董金皋🥷🏽,曾凡力. 一株侵占木黴及其微生物菌劑、製備方法和應用. 發明專利, ZL202211083689.X🍊,2023-08-01
2. 錢欣雨,田賜,張利輝👩🏻🎓,郝誌敏,董金皋. 一種死谷芽孢桿菌及其應用☞,發明專利,ZL202110931495.X🔎,2022-11-26
3. 郝誌敏,曾凡力,胡玉笑,賈艷榮📀,趙相東,董金皋🏆,申珅. 一種基因無痕編輯載體及其在生物體基因編輯中的應用. 發明專利,ZL201810524747.5📀,2021-7-13
4. 郝誌敏🏄🏼,王會敏,董金皋,梁海龍,申珅🚽💻,曾凡力. 一種多粘類芽孢桿菌、應用及微生物菌劑🧑🏼🎓、粉劑和顆粒劑. 發明專利🆑,ZL201811452399.1,2021-06-08